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Thursday, June 20, 2013

What is Biological valves?

** Biological valves are valves of animals, which 

undergo some chemical methods in alignment to 

make them apt for implantation in the human 

heart.(pig)

** The pig heart is most alike to the human heart, 

and thus represents the best anatomical fit for 

replacement. Implantation of a porcine valve is a 

kind of xenotransplantation.




** Biological valves are stiffer than natural heart 

valves due to the remedy process.

** Other kind of biological valve utilizes biological 

tissue to make leaflets that are stitched into a steel 

border. This tissue is normally gathered from the 

Pericardial Sac of either Bovine (cows) or Equine 

(horses).

Functional requirements of heart valve prostheses

1. Minimal regurgitation:

 **For demonstration, closure regurgitation 

through the mitral valve would result in some 

body-fluid decrease from the left ventricle to the 

left atrium as the mitral valve closes.This means 

that the allowance of body-fluid lost upstream as 

the valve closes is little.

2. Minimal transvalvular pressure gradient:

** Natural heart valves have a reduced transvalvular 

force slope as they present small obstruction to 

the flow through themselves, normally less than 16 

mmHg. A desirable attribute of heart valve 

prostheses is that their transvalvular force slope is 

as small as possible.

3. Non-thrombogenic

4.Self-repairing
5. Rapid dynamic response.

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