What is Biological
valves?
** Biological valves are valves of animals, which
undergo some chemical methods in alignment to
make them apt for implantation in the human
heart.(pig)
** The pig heart is most alike to the human heart,
and thus represents the best anatomical fit for
replacement. Implantation of a porcine valve is a
kind of xenotransplantation.
** Biological valves are stiffer than natural heart
valves due to the remedy process.
** Other kind of biological valve utilizes biological
tissue to make leaflets that are stitched into a steel
border. This tissue is normally gathered from the
Pericardial Sac of either Bovine (cows) or Equine
(horses).
Functional
requirements of heart valve prostheses
1. Minimal regurgitation:
**For demonstration, closure regurgitation
through the mitral valve would result in some
body-fluid decrease from the left ventricle to the
left atrium as the mitral valve closes.This means
that the allowance of body-fluid lost upstream as
the valve closes is little.
2. Minimal transvalvular pressure gradient:
** Natural heart valves have a reduced transvalvular
force slope as they present small obstruction to
the flow through themselves, normally less than 16
mmHg. A desirable attribute of heart valve
prostheses is that their transvalvular force slope is
as small as possible.
3. Non-thrombogenic
4.Self-repairing
5. Rapid dynamic response.
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